From Pittsburgh:

Take 22 E to 119 N. At Indiana Stay on 119 N. When the 4 lane turns into a 2 lane (towards Punxsutawney), the nursery is approximately 2 miles on the right.

From Harrisburg:

PA Turnpike West to Bedford.  Take 99/220 N to Altoona. Take 22 West to Ebensburg. Take 422 West to Indiana.  Take 119 N.  When the 4 lane turns into a 2 lane (towards Punxsutawney), the nursery is approximately 2 miles on the right.

From Washington/Baltimore:

70 W to PA Turnpike West (76/70 W).  Follow directions above form Harrisburg.

From Buffalo:

Scenic Route: 219 S to Dubois, PA.  119 S to Indiana Nursery will be on your left. Not so Scenic Route: 90 W to 79 S to 422 E towards Butler.  Continue on 422 E to Indiana.  Take 119 N towards Punxsutawney.  When the 4 lane turns into a 2 lane (towards Punxsutawney), the nursery is approximately 2 miles on the right.

From Cleveland:

80 E to 79 S to 422 E towards Butler.  Continue on 422 E to Indiana.  Take 119 N towards Punxsutawney.  When the 4 lane turns into a 2 lane (towards Punxsutawney), the nursery is approximately 2 miles on the right.